Dr. Jordi Duran
I am a Principal Investigator and Associate Professor at Institut Químic de Sarrià (IQS) - Ramon Llull University (URL), and Associate Researcher at IBEC Barcelona. My research group is devoted to the study of brain metabolism, in particular the physiological roles of glycogen in brain functioning and its pathological role in neurodegenerative conditions like Lafora disease. I am also scientific advisor of the charity foundation Fundació La Marató de TV3.
News
Oct 17, 2023. Setmana de la Ciència
We have participated in "Setmana de la Ciència" to disseminate scientific research among the general public.
https://setmanaciencia.fundaciorecerca.cat/frontend/detall_activitat.asp?ID=4600
Oct 14, 2023. Lund University
We have participated in the Wallenberg Center for Molecular Medicine Research School, Lund University
Oct 3, 2023. Epilepsy Sparks
Hear of the ultra-rare, devastating, terminal epilepsy Lafora Disease and the exciting research taking place to try and improve and save the lives of the children affected.
https://www.youtube.com/watch?v=M6-GW-VfVJo
https://www.torierobinson.com/epilepsy-sparks-insights/jordi-duran-lafora-diesease
Sep 21, 2023. Barcelona
Una teràpia gènica per a la malaltia de Lafora, via IQS Barcelona
Jul 14, 2023. VibeCast
Podcast on the challenges funding rare disease research, Lafora disease and Fighting the Rare VibeCast Ep 19
Jul 04, 2023 - New article
Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis - We show that excess #glycogen in #astrocytes plays a toxic role not only in #laforadisease but also in another neurodegenerative condition like #ALS
Jun 26, 2023. Barcelona
Fighting the Rare presentation at IQS Barcelona
Jun 21, 2023. CheckRare
Interview by 'CheckRare'. Dr. Jordi Duran and Niki Markou, discuss the documentary Fighting the Rare and the symptoms and pathophysiology of Lafora disease.
Apr 15, 2023 - Project Granted
We have received a Project Grant award from Fundación Ramón Areces. We will try to speed up the search for an effective cure for #laforadisease
Feb 24, 2023 - New article
Role of Astrocytes in the Pathophysiology of Lafora Disease and Other Glycogen Storage Disorders - A review on how the accumulation of #glycogen in astrocytes contributes to #laforadisease and other neurodegenerative conditions.
Feb 17, 2023 - La Marató
En 31 anys de solidaritat, La Marató de TV3 i Catalunya Ràdio ha finançat prop de 1.000 projectes de recerca que han aportat millores en la qualitat i l'esperança de vida de tots nosaltres.
https://www.ccma.cat/tv3/alacarta/programa/doctor-jordi-duran
Jan 30, 2023 - New article
Active Glycogen Synthase in the Liver Prevents High-Fat Diet-Induced Glucose Intolerance, Decreases Food Intake, and Lowers Body Weight.
Jan 27, 2023 - Fighting the Rare
Shooting Fighting the Rare at IRB Barcelona
https://twitter.com/FightingTheRare/status/1619004690485882881?s=20
Jan 18, 2023 - Fighting the Rare
Shooting Fighting the Rare at IQS Barcelona
https://twitter.com/IQSbarcelona/status/1615715773493792770?s=20
Dec 5, 2022 - Fighting the Rare
Shooting Fighting the Rare at CCCB Barcelona
https://twitter.com/FightingTheRare/status/1599795805790949376?s=20
Sep 28, 2022 - Fighting the Rare
Shooting Fighting the Rare at Lafora disease Symposium (San Diego, USA)
https://twitter.com/DrJordiDuran/status/1574898889387233280?s=20
Sep 09, 2022 - New article
Hepatic overexpression of protein targeting to glycogen attenuates obesity and improves hyperglycemia in db/db mice
Jun 03, 2022 - New article
Malin restoration as proof of concept for gene therapy for Lafora disease - we identify malin restoration as the first therapeutic strategy to show effectiveness when applied at advanced stages of Lafora disease
Feb 17, 2022 - IQS interview
Brain Glycogen and Neurodegenerative Diseases
https://techtransfer.iqs.edu/en/news/brain-glycogen-and-neurodegenerative-diseases/
Jan 1, 2022 - New article
Lack of p62 Impairs Glycogen Aggregation and Exacerbates Pathology in a Mouse Model of Myoclonic Epilepsy of Lafora - we demonstrate that p62 participates in the formation of glycogen aggregates to reduce the deleterious consequences of its accumulation in the brain.
Apr 20, 2021 - New article
Scientists at IRB Barcelona discover the cause of neurodegeneration in Lafora disease
Astrocytic glycogen accumulation drives the pathophysiology of neurodegeneration in Lafora disease - we demonstrate the contribution of astrocytes to the pathology of Lafora disease.